WO2023131811 - POLYCISTRONIC EXPRESSION OF GUT PEPTIDES

National phase entry:
Publication Number WO/2023/131811
Publication Date 13.07.2023
International Application No. PCT/IB2022/000815
International Filing Date 15.12.2022
Title **
[English] POLYCISTRONIC EXPRESSION OF GUT PEPTIDES
[French] EXPRESSION POLYCISTRONIQUE DE PEPTIDES INTESTINAUX
Applicants **
MEIRAGTX UK II LIMITED
Inventors
GUO, Xuecui
FORBES, Alexandria
Priority Data
63/361,399   15.12.2021   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting4462
EPO Filing, Examination, Granting69715
Japan Filing, Examination, Granting4283
South Korea Filing, Examination, Granting6291
USA Filing, Examination, Granting20940
MasterCard Visa
Total: 105,691

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Abstract[English] Provided herein are monocistronic, bicistronic, and polycistronic expression constructs for the expression of gut peptides and pharmaceutical compositions comprising such expression constructs. Also provided are methods of using such expression constructs, for example, for inducing satiation in a subject in need thereof or for treating obesity in a subject in need thereof.[French] L'invention concerne des constructions d'expression monocistroniques, bicistroniques et polycistroniques pour l'expression de peptides intestinaux et des compositions pharmaceutiques comprenant de telles constructions d'expression. L'invention concerne également des méthodes d'utilisation de telles constructions d'expression, par exemple, pour induire la satiété chez un sujet le nécessitant ou pour traiter l'obésité chez un sujet le nécessitant.

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