WO2023111686 - APTAMERS AND SMALL MOLECULE LIGANDS
National phase entry:
Publication Number
WO/2023/111686
Publication Date
22.06.2023
International Application No.
PCT/IB2022/000762
International Filing Date
15.12.2022
Title **
[English]
APTAMERS AND SMALL MOLECULE LIGANDS
[French]
APTAMÈRES ET LIGANDS À PETITES MOLÉCULES
Applicants **
MEIRAGTX UK II LIMITED
Inventors
GUO, Xuecui
FORBES, Alexandria
LIU, Kevin, G.
KIM, Ji-in
Priority Data
63/361,400
15.12.2021
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
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| Number of Office Actions | * |
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International Searching Authority |
EPO
* |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
* |
| Type of Assignment |
The Standard Agent's Assignment
* |
| Applicant's Legal Status |
Legal Entity
* |
| * | |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 5335 | |
| EPO | Filing, Examination, Granting | 51630 | |
| Japan | Filing, Examination, Granting | 3743 | |
| South Korea | Filing, Examination, Granting | 4911 | |
| USA | Filing, Examination, Granting | 33340 |
Total:
98,959
The term for entry into the National Phase has expired. This quotation is for informational purposes only
Abstract[English]
The present disclosure provides aptamers that bind to certain small molecules. Also contemplated are riboswitches and polynucleotide cassettes for regulating the expression of a target gene, wherein the polynucleotide cassettes comprise the aptamers disclosed herein. Further provided are small molecules that bind to the aptamers disclosed herein and are modulators of target gene expression where the target gene contains a riboswitch comprising an aptamer described herein.[French]
La présente divulgation concerne des aptamères qui se lient à certaines petites molécules. La divulgation concerne également des riboswitchs et des cassettes polynucléotidiques permettant de réguler l'expression d'un gène cible, les cassettes polynucléotidiques comprenant les aptamères présentement divulgués. La divulgation concerne en outre de petites molécules qui se lient aux aptamères présentement divulgués et qui sont des modulateurs de l'expression génique cible, le gène cible contenant un riboswitch comprenant un aptamère présentement décrit.