WO2022079612 - METHOD AND COMPOUNDS FOR TREATING DIABETES AND ASSOCIATED METABOLIC DISEASES

National phase entry:
Publication Number WO/2022/079612
Publication Date 21.04.2022
International Application No. PCT/IB2021/059370
International Filing Date 12.10.2021
Title **
[English] METHOD AND COMPOUNDS FOR TREATING DIABETES AND ASSOCIATED METABOLIC DISEASES
[French] MÉTHODE ET COMPOSÉS POUR LE TRAITEMENT DU DIABÈTE ET DES MALADIES MÉTABOLIQUES ASSOCIÉES
Applicants **
BETAVIVE LTD.
Inventors
PALTI, Yoram
ZURI, Dotan
Priority Data
63/090,943   13.10.2020   US
63/234,862   19.08.2021   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting1408
EPO Filing, Examination, Granting8803
Japan Filing, Examination, Granting1626
South Korea Filing, Examination, Granting1125
USA Filing, Examination, Granting3490
MasterCard Visa
Total: 16,452

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] The disclosure provides for compounds, compositions, and methods of use thereof for treating diabetes (e.g., type 1 diabetes, type 2 diabetes). In some aspects, methods comprise administering first, second, third, fourth, and fifth daily doses of insulin-like growth factor 2 ("IGF-2") or a variant thereof to the subject at respective first, second, third, fourth, and fifth different times, wherein each of the daily doses comprises at least 65 µg of IGF-2. In other aspects, compounds, compositions, and methods containing IGF-2 or variants thereof are used for treating a disorder in a patient in need thereof, such as type 1 or type 2 diabetes.[French] La présente divulgation concerne des composés, des compositions et leurs méthodes d'utilisation pour le traitement du diabète (p. ex., du diabète de type 1 ou de type 2). Selon certains aspects, les méthodes comprennent l'administration d'une première, d'une deuxième, d'une troisième, d'une quatrième et d'une cinquième doses quotidiennes de facteur de croissance de type insuline 2 (« IGF-2 ») ou d'un variant de celui-ci au sujet à des premier, deuxième, troisième, quatrième et cinquième moments différents, chacune des doses journalières comprenant au moins 65 µg d'IGF-2. Selon d'autres aspects, les composés, les compositions et les méthodes impliquant l'IGF-2 ou des variants de celui-ci sont utilisés pour traiter une affection chez un patient qui en a besoin, p. ex., le diabète de type 1 ou de type 2.

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