WO2026008836 - GLP-1 DERIVATIVES AND USES THEREOF

National phase entry is expected:
Publication Number WO/2026/008836
Publication Date 08.01.2026
International Application No. PCT/EP2025/069132
International Filing Date 04.07.2025
Title **
[English] GLP-1 DERIVATIVES AND USES THEREOF
[French] DÉRIVÉS DE GLP-1 ET LEURS UTILISATIONS
Applicants **
NOVO NORDISK A/S
Inventors
LINDEROTH, Lars
REEDTZ-RUNGE, Steffen
WALDHOER, Maria
KOFOED, Jacob
Priority Data
24186705.0   05.07.2024   EP
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2194
EPO Filing, Examination, Granting8791
Japan Filing, Examination, Granting2161
South Korea Filing, Examination, Granting2056
USA Filing, Examination, Granting4740
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Total: 19,942
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Abstract[English] The present invention relates to novel GLP-1 derivatives that are activating the GLP- 1 receptor in a way that favours a cAMP response and has an impaired beta-arrestin recruitment. More particular the present invention relates to such GLP-1 derivatives and their use for treatment of diseases such as diabetes and obesity.[French] La présente invention concerne de nouveaux dérivés de GLP-1 qui activent le récepteur GLP-1 d'une manière qui favorise une réponse cAMP et a un recrutement de bêta-arrestine altéré. Plus particulièrement, la présente invention concerne de tels dérivés de GLP-1 et leur utilisation pour le traitement de maladies telles que le diabète et l'obésité.

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