WO2026003088 - SCAFFOLD FREE CARTILAGE IMPLANTS
National phase entry is expected:
Publication Number
WO/2026/003088
Publication Date
02.01.2026
International Application No.
PCT/EP2025/067934
International Filing Date
25.06.2025
Title **
[English]
SCAFFOLD FREE CARTILAGE IMPLANTS
[French]
IMPLANTS DE CARTILAGE EXEMPTS D'ÉCHAFAUDAGE
Applicants **
KATHOLIEKE UNIVERSITEIT LEUVEN
Inventors
PAPANTONIOU, Ioannis
DIMOPOULOS, Andreas
Priority Data
24184339.0
25.06.2024
EP
Application details
| Total Number of Claims/PCT | * |
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International Searching Authority |
EPO
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| * | |
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2276 | |
| EPO | Filing, Examination, Granting | 10728 | |
| Japan | Filing, Examination, Granting | 2296 | |
| South Korea | Filing, Examination, Granting | 2306 | |
| USA | Filing, Examination, Granting | 4740 |
Total:
22,346
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Abstract[English]
The invention relates to methods of preparing an implant for bone repair, the method comprising the steps of expanding periosteum derived cells, mixing the expanded periosteum derived cells with a partially cross-linked sodium alginate solution, forming the alginate solution and the cells into a shaped construct, differentiating the cells in the shaped construct towards chondrogenic differentiation, and dissolving crosslinked alginate with a calcium chelating agent.[French]
L'invention concerne des procédés de préparation d'un implant pour la réparation osseuse, le procédé comprenant les étapes consistant à expanser des cellules dérivées de périoste, à mélanger les cellules dérivées de périoste expansées avec une solution d'alginate de sodium partiellement réticulée, à former la solution d'alginate et les cellules dans une construction façonnée, à différencier les cellules dans la construction façonnée vers une différenciation chondrogénique, et à dissoudre de l'alginate réticulé avec un agent chélatant le calcium.