WO2025237891 - QUINOLINE-2-CARBOXAMIDE DERIVATIVES AS RAD51 INHIBITORS FOR THE TREATMENT OF CANCER

National phase entry is expected:
Publication Number WO/2025/237891
Publication Date 20.11.2025
International Application No. PCT/EP2025/062878
International Filing Date 12.05.2025
Title **
[English] QUINOLINE-2-CARBOXAMIDE DERIVATIVES AS RAD51 INHIBITORS FOR THE TREATMENT OF CANCER
[French] DÉRIVÉS DE QUINOLÉINE-2-CARBOXAMIDE UTILISÉS EN TANT QU'INHIBITEURS DE RAD51 POUR LE TRAITEMENT DU CANCER
Applicants **
NERVIANO MEDICAL SCIENCES S.R.L.
Inventors
PICCONI, Pietro
MIRIZZI, Danilo
BUFFA, Laura
ORRENIUS, Sten Christian
ASA, Daniela Silvia
Priority Data
24175771.5   14.05.2024   EP
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting6104
EPO Filing, Examination, Granting30774
Japan Filing, Examination, Granting2892
South Korea Filing, Examination, Granting3473
USA Filing, Examination, Granting31440
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Total: 74,683
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Abstract[English] The present invention relates to substituted quinoline derivatives of formula (I) as inhibitors of the activity of RAD51 for the treatment of cancer, cell proliferative disorders or immune disorders.[French] La présente invention concerne des dérivés de quinoléine substitués de formule (I) utilisés en tant qu'inhibiteurs de l'activité de RAD51 pour le traitement du cancer, de troubles de prolifération cellulaire ou de troubles immunitaires.

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