WO2025180875 - METHOD FOR PRODUCTION OF GENE THERAPY VEHICLES IN MAMMALIAN CELLS
National phase entry is expected:
Publication Number
WO/2025/180875
Publication Date
04.09.2025
International Application No.
PCT/EP2025/054188
International Filing Date
17.02.2025
Title **
[English]
METHOD FOR PRODUCTION OF GENE THERAPY VEHICLES IN MAMMALIAN CELLS
[French]
PROCÉDÉ DE PRODUCTION DE VÉHICULES DE THÉRAPIE GÉNIQUE DANS DES CELLULES DE MAMMIFÈRE
Applicants **
UNIVERSITAT AUTONOMA DE BARCELONA
Inventors
BOSCH MOLIST, Laia
CERVERA GRACIA, Laura
GARCIA MARTINEZ, Miguel
GODIA CASABLANCAS, Francesc
LAVADO GARCIA, Jesus
LEON MADRENAS, Xavier
Priority Data
24159714.5
26.02.2024
EP
Application details
| Total Number of Claims/PCT | * |
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International Searching Authority |
EPO
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2278 | |
| EPO | Filing, Examination, Granting | 9785 | |
| Japan | Filing, Examination, Granting | 2241 | |
| South Korea | Filing, Examination, Granting | 2166 | |
| USA | Filing, Examination, Granting | 4740 |
Total:
21,210
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Abstract[English]
The present invention relates to a method for production of viruses, viral derivatives, extracellular vesicles (EVs), such as exosomes or microvesicles, or recombinant viral vectors in a cell line, comprising the step of overexpressing SNAP47, VPS37B, SMPD3A/SNAP47, or CD63 in combination with VPS37B, SNAP47 or SMPD3A in said cell line, as well as to a cell line stably overexpressing at least one of these genes.[French]
La présente invention concerne un procédé de production de virus, de dérivés viraux, de vésicules extracellulaires (VE), telles que des exosomes ou des microvésicules, ou des vecteurs viraux recombinants dans une lignée cellulaire, comprenant l'étape de surexpression de SNAP47, VPS37B, SMPD3A/SNAP47, ou CD63 en combinaison avec VPS37B, SNAP47 ou SMPD3A dans ladite lignée cellulaire, ainsi qu'une lignée cellulaire surexprimant de manière stable au moins l'un de ces gènes.