WO2025108925 - IMPROVED PRODUCTION OF BACTERIAL CELLULOSE

National phase entry is expected:
Publication Number WO/2025/108925
Publication Date 30.05.2025
International Application No. PCT/EP2024/082812
International Filing Date 19.11.2024
Title **
[English] IMPROVED PRODUCTION OF BACTERIAL CELLULOSE
[French] PRODUCTION AMÉLIORÉE DE CELLULOSE BACTÉRIENNE
Applicants **
ETH ZURICH
Inventors
STUDART, André
DEMELLO, Andrew
STAVRAKIS, Stavros
LAURENT, Julie
KAN, Anton
JAIN, Ankit
STEINACHER, Mathias
ENRRIQUEZ, Nadia
Priority Data
23210958.7   20.11.2023   EP
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2139
EPO Filing, Examination, Granting8772
Japan Filing, Examination, Granting2166
South Korea Filing, Examination, Granting1965
USA Filing, Examination, Granting4740
MasterCard Visa
Total: 19,782
Abstract[English] The invention concerns a genetically modified cellulose producing bacterial strain comprising a reduction in expression of native gene encoding a ClpS polypeptide, or a deletion of the native gene encoding a native ClpS polypeptide, or comprising expressing or overexpressing a gene encoding a ClpA polypeptide containing a mutation or a deletion in the ClpS-binding region of said polypeptide, and/or expressing or overexpressing a gene encoding a ClpS polypeptide containing a mutation or deletion in the ClpA-binding region of said polypeptide, causing an alteration of binding affinity between the ClpS polypeptide and the ClpA polypeptide.[French] L'invention concerne une souche bactérienne productrice de cellulose génétiquement modifiée, comprenant une réduction de l'expression du gène natif codant pour un polypeptide ClpS, ou une délétion du gène natif, codant pour un polypeptide ClpS natif, ou comprenant l'expression ou la surexpression d'un gène codant pour un polypeptide ClpA, contenant une mutation ou une délétion dans la région de liaison ClpS dudit polypeptide et/ou l'expression ou la surexpression d'un gène, codant pour un polypeptide ClpS, contenant une mutation ou une délétion dans la région de liaison ClpA dudit polypeptide, provoquant une altération de l'affinité de liaison entre le polypeptide ClpS et le polypeptide ClpA.

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