WO2025093589 - HETEROARYL AMIDE DERIVATIVES AS SODIUM CHANNEL INHIBITORS
National phase entry is expected:
Publication Number
WO/2025/093589
Publication Date
08.05.2025
International Application No.
PCT/EP2024/080663
International Filing Date
30.10.2024
Title **
[English]
HETEROARYL AMIDE DERIVATIVES AS SODIUM CHANNEL INHIBITORS
[French]
DÉRIVÉS D'AMIDE HÉTÉROARYLE UTILISÉS EN TANT QU'INHIBITEURS DE CANAUX SODIQUES
Applicants **
CHIESI FARMACEUTICI S.P.A.
Inventors
FIORELLI, Claudio
FOSSATI, Giacomo
MENGOZZI, Luca
MOSCA, Giampaolo
PATACCHINI, Riccardo
RIZZI, Andrea
Priority Data
23207536.6
02.11.2023
EP
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
| * | |
| Number of Office Actions | * |
| * | |
International Searching Authority |
EPO
* |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
* |
| Type of Assignment |
The Standard Agent's Assignment
* |
| Applicant's Legal Status |
Legal Entity
* |
| * | |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
* |
| Patent Delivery |
Send the Letters Patent by Courier
* |
| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 3545 | |
| EPO | Filing, Examination, Granting | 24852 | |
| Japan | Filing, Examination, Granting | 3025 | |
| South Korea | Filing, Examination, Granting | 3619 | |
| USA | Filing, Examination, Granting | 26790 |
Total:
61,831
The term for entry into the National Phase has expired. This quotation is for informational purposes only
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Abstract[English]
The present invention generally relates to compounds of formula (I) inhibiting sodium channel (NaV) activity; particularly, the invention relates to compounds that are heteroaryl amide derivatives, including zwitterionic forms and pharmaceutically acceptable salts thereof, methods of preparing such compounds, and therapeutic use thereof. The compounds of the invention may be useful for instance in the treatment of many disorders associated with NaV, such as respiratory diseases.[French]
La présente invention concerne de manière générale des composés de formule (I) inhibant l'activité du canal sodique (NaV) ; en particulier, elle concerne des composés qui sont des dérivés d'amide hétéroaryle, y compris des formes zwitterioniques et des sels pharmaceutiquement acceptables de ceux-ci, des procédés de préparation de tels composés, et leur utilisation thérapeutique. Les composés de l'invention peuvent être utiles, par exemple, dans le traitement de nombreux troubles associés au NaV, tels que des maladies respiratoires.