WO2023194069 - MAGNETIC IMMUNOASSAY DEVICE
National phase entry is expected:
Publication Number
WO/2023/194069
Publication Date
12.10.2023
International Application No.
PCT/EP2023/056818
International Filing Date
16.03.2023
Title **
[English]
MAGNETIC IMMUNOASSAY DEVICE
[French]
DISPOSITIF DE DOSAGE IMMUNOLOGIQUE MAGNÉTIQUE
Applicants **
SENSIRION AG
Inventors
STREIFF, Matthias
HUBER, Deborah
BÜRGI, Lukas
KELLER, Dino
Priority Data
22166440.2
04.04.2022
EP
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
| * | |
| Number of Office Actions | * |
| * | |
International Searching Authority |
EPO
* |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
* |
| Type of Assignment |
The Standard Agent's Assignment
* |
| Applicant's Legal Status |
Legal Entity
* |
| * | |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
* |
| Patent Delivery |
Send the Letters Patent by Courier
* |
| Translation |
|
* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 1882 | |
| EPO | Filing, Examination, Granting | 8218 | |
| Japan | Filing, Examination, Granting | 1947 | |
| South Korea | Filing, Examination, Granting | 1532 | |
| USA | Filing, Examination, Granting | 4740 |
Total:
18,319
The term for entry into the National Phase has expired. This quotation is for informational purposes only
Abstract[English]
The present invention relates to a method and a device for determining a bond strength of functionalized magnetic labels (1) to a functionalized detection surface (2) in an immunoassay. The labels (1) are transported to the surface (2) for an incubation step. Subsequently, the labels (1) are manipulated by a magnetic force field and initial positions and dissociation times from the surface (2) of the labels (1) are recorded. These dissociation times are then compared to pre-computed time-spans per position, the time-spans chosen such that the probability of dissociation of a label (1) not specifically bound at a position before said time span has elapsed is greater than a predetermined threshold. If the dissociation time is greater than said time span, the label (1) is designated as specifically bound to the surface (2).[French]
La présente invention se rapporte à un procédé et à un dispositif de détermination d'une force de liaison d'étiquettes magnétiques fonctionnalisées (1) à une surface de détection fonctionnalisée (2) dans un dosage immunologique. Les étiquettes (1) sont transportées vers la surface (2) pour une étape d'incubation. Ensuite, les étiquettes (1) sont manipulées par un champ de force magnétique et des positions initiales et des temps de dissociation par rapport à la surface (2) des étiquettes (1) sont enregistrés. Lesdits temps de dissociation sont ensuite comparés à des intervalles de temps pré-calculés par position, les intervalles de temps étant choisis de telle sorte que la probabilité de dissociation d'une étiquette (1) non spécifiquement liée à une position avant l'écoulement dudit intervalle de temps soit supérieure à un seuil prédéterminé. Si le temps de dissociation est supérieur audit intervalle de temps, l'étiquette (1) est désignée comme étant liée spécifiquement à la surface (2).