WO2023179905 - COMBINATION OF 5-AMINO-2,3-DIHYDRO-1,4-PHTHALAZINEDIONE AND A FUMARIC ACID ESTER

National phase entry:
Publication Number WO/2023/179905
Publication Date 28.09.2023
International Application No. PCT/EP2023/000022
International Filing Date 23.03.2023
Title **
[English] COMBINATION OF 5-AMINO-2,3-DIHYDRO-1,4-PHTHALAZINEDIONE AND A FUMARIC ACID ESTER
[French] COMBINAISON DE 5-AMINO-2,3-DIHYDRO -1,4-PHTALAZINEDIONE ET D'UN ESTER D'ACIDE FUMARIQUE
Applicants **
METRIOPHARM AG
Inventors
BRYSCH, Wolfgang
SCHUMANN, Sara
BREMBECK, Felix
LUDESCHER, Beate
VON WEGERER, Jörg
Priority Data
22000080.6   25.03.2022   EP
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2238
EPO Filing, Examination, Granting6855
Japan Filing, Examination, Granting2233
South Korea Filing, Examination, Granting2110
USA Filing, Examination, Granting4740
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Total: 18,176

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] The present application relates to a combination of 5-amino-2,3-dihydro-1,4- phthalazinedione or one of its pharmaceutically acceptable salts and at least one fumaric acid ester or a pharmaceutically acceptable salt thereof. In particular, the invention relates to the use of 5-amino-2,3-dihydro-1,4-phthalazinedione sodium salt in said pharmaceutical combination. Pharmaceutical compositions and advantageous formulation techniques are disclosed.[French] La présente invention concerne une combinaison de 5-amino-2,3-dihydro -1,4-phtalazinedione ou d'un de ses sels pharmaceutiquement acceptables et d'au moins un ester d'acide fumarique ou d'un sel pharmaceutiquement acceptable de celui-ci. En particulier, l'invention concerne l'utilisation de sel de sodium de 5-amino-2,3-dihydro -1,4-phtalazinedione dans ladite combinaison pharmaceutique. L'invention concerne également des compositions pharmaceutiques et des techniques de formulation avantageuses.