WO2023052556 - METHODS OF INACTIVATING VIRAL CONTAMINANTS WITH A MIXTURE OF SOLVENT AND DETERGENT

National phase entry:
Publication Number WO/2023/052556
Publication Date 06.04.2023
International Application No. PCT/EP2022/077206
International Filing Date 29.09.2022
Title **
[English] METHODS OF INACTIVATING VIRAL CONTAMINANTS WITH A MIXTURE OF SOLVENT AND DETERGENT
[French] PROCÉDÉS D'INACTIVATION DE CONTAMINANTS VIRAUX AVEC UN MÉLANGE DE SOLVANT ET DE DÉTERGENT
Applicants **
ICHNOS SCIENCES SA
Inventors
CAHUZAC, Laure
DUARTE, Lionel
DURET, Anais
Priority Data
21200257.0   30.09.2021   EP
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2084
EPO Filing, Examination, Granting8323
Japan Filing, Examination, Granting2181
South Korea Filing, Examination, Granting2043
USA Filing, Examination, Granting4740
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Total: 19,371

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Abstract[English] The present invention relates to methods of viral inactivation with a mixture of solvent and detergent. In particular, the present invention is directed to a method for preparing a virus- inactivated polypeptide solution wherein a polypeptide material is first loaded into an affinity chromatography column then incubated with said mixture of a solvent and a detergent within the affinity chromatography column.[French] La présente invention concerne des procédés d'inactivation virale avec un mélange de solvant et de détergent. En particulier, la présente invention concerne un procédé de préparation d'une solution polypeptidique inactivée par un virus dans laquelle une substance polypeptidique est d'abord chargée dans une colonne de chromatographie d'affinité puis incubée avec ledit mélange de solvant et de détergent dans la colonne de chromatographie d'affinité.

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