WO2024056196 - ANTIBODIES AND METHOD OF USE FOR P. GINGIVALIS
National phase entry:
Publication Number
WO/2024/056196
Publication Date
21.03.2024
International Application No.
PCT/EP2022/075842
International Filing Date
16.09.2022
Title **
[English]
ANTIBODIES AND METHOD OF USE FOR P. GINGIVALIS
[French]
ANTICORPS ET MÉTHODES D'UTILISATION DE P. GINGIVALIS
Applicants **
SHI, Xiaoju
XU, Maria Xing
QJM BIOINFORMATION LTD
ZHENJIANG YANGTZE GREEN BIOTECHNOLOGY LTD
Inventors
SHI, Xiaoju
XU, Maria Xing
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
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International Searching Authority |
EPO
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| * | |
| * | |
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2947 | |
| EPO | Filing, Examination, Granting | 18132 | |
| Japan | Filing, Examination, Granting | 2636 | |
| South Korea | Filing, Examination, Granting | 2900 | |
| USA | Filing, Examination, Granting | 19790 |

Total:
46,405
The term for entry into the National Phase has expired. This quotation is for informational purposes only
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Abstract[English]
The present disclosure provides monoclonal antibodies, and method of use thereof, for diagnosing and/or treating P. gingivalis infection and/or chronic diseases resulted from or associated with such infection. Specific antigen¬ antibody reaction regions on each P. gingivalis outer membrane protein are also identified and used for developing vaccines for prevention and treatment. The monoclonal antibodies of the present disclosure cross-react with different antigen regions of different P. gingivalis outer membrane protein. Animal models and diagnostic kits for serological evaluation and assessment of prognosis and treatment effectiveness after P. gingivalis infection are also provided.[French]
La présente divulgation concerne des anticorps monoclonaux, ainsi qu'une méthode d'utilisation de ceux-ci dans le diagnostic et/ou le traitement d'une infection par P. gingivalis et/ou de maladies chroniques résultant d'une telle infection ou associées à celle-ci. Des régions de réaction anticorps-antigène spécifiques sur chaque protéine de membrane externe de P. gingivalis sont également identifiées et utilisées pour développer des vaccins destinés à la prévention et au traitement. Les anticorps monoclonaux de la présente divulgation réagissent de manière croisée avec différentes régions
antigéniques de différentes protéines de membrane externe de P. gingivalis. L'invention concerne également des modèles animaux et des kits de diagnostic pour l'évaluation sérologique et l'estimation du pronostic et de l'efficacité du traitement après une infection par P. gingivalis.