WO2023020732 - METHODS AND DEVICES FOR SIMULATING CHARGED-PARTICLE TRANSPORT IN AN EXTERNAL MAGNETIC FIELD, WITH APPLICATIONS TO RADIOTHERAPY PLANNING

National phase entry:
Publication Number WO/2023/020732
Publication Date 23.02.2023
International Application No. PCT/EP2022/066512
International Filing Date 16.06.2022
Title **
[English] METHODS AND DEVICES FOR SIMULATING CHARGED-PARTICLE TRANSPORT IN AN EXTERNAL MAGNETIC FIELD, WITH APPLICATIONS TO RADIOTHERAPY PLANNING
[French] MÉTHODES ET DISPOSITIFS POUR SIMULER UN TRANSPORT DE PARTICULES CHARGÉES DANS UN CHAMP MAGNÉTIQUE EXTERNE, AVEC DES APPLICATIONS POUR LA PLANIFICATION DE RADIOTHÉRAPIE
Applicants **
RAYSEARCH LABORATORIES AB
Inventors
ANGERUD, Agnes
FÄLTH, Claes
Priority Data
21192314.9   20.08.2021   EP
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China Filing, Examination, Granting2044
EPO Filing, Examination, Granting8395
Japan Filing, Examination, Granting2230
South Korea Filing, Examination, Granting2232
USA Filing, Examination, Granting4740
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Abstract[English] which depends on the unit direction vector u(t) and further depends nonlinearly on a motion variable n(t) of the particle. According to the method, Newton's second law is solved using an implicit finite-difference method in which, for the duration of a time step, the force term is approximated by its value for interpolated values of the unit direction vector and the motion variable, wherein the interpolated value of each quantity is a combination of that quantity's values at the endpoints t, t + Δt of the time step. The method is useful for calculating the dose when a treatment plan P is delivered to a patient 310 by a radiation delivery system 300. (Fig. 3)[French] qui dépend du vecteur de direction unitaire u(t) et dépend en outre non linéairement d’une variable de mouvement n(t) de la particule. Selon la méthode, la seconde loi de Newton est résolue à l'aide d'une méthode implicite des différences finies dans laquelle, pour la durée d'une étape de temps, le terme de force est approximé par sa valeur pour des valeurs interpolées du vecteur de direction unitaire et de la variable de mouvement, la valeur interpolée de chaque quantité étant une combinaison des valeurs de la quantité aux points d'extrémité t, t + Δt de l'étape de temps. La méthode est utile pour calculer la dose lorsqu'un plan de traitement P est délivré à un patient 310 par un système de distribution de rayonnement 300. (Fig. 3)