WO2023104327 - COMBINATION OF 5-AMINO-2,3-DIHYDRO-1,4-PHTALAZINEDIONE AND A 6'-METHOXYCINCHONAN-9-OL FOR USE IN THE TREATMENT OF CORONAVIRAL INFECTIONS

National phase entry:
Publication Number WO/2023/104327
Publication Date 15.06.2023
International Application No. PCT/EP2022/000110
International Filing Date 08.12.2022
Title **
[English] COMBINATION OF 5-AMINO-2,3-DIHYDRO-1,4-PHTALAZINEDIONE AND A 6'-METHOXYCINCHONAN-9-OL FOR USE IN THE TREATMENT OF CORONAVIRAL INFECTIONS
[French] COMBINAISON DE 5-AMINO-2,3-DIHYDRO-1,4-PHTALAZINEDIONE ET D'UN 6'-MÉTHOXYCINCHONANE-9-OL POUR UNE UTILISATION DANS LE TRAITEMENT D'INFECTIONS CORONAVIRALES
Applicants **
METRIOPHARM AG
Inventors
BRYSCH, Wolfgang
SCHUMANN, Sara
LUDESCHER, Beate
VON WEGERER, Jörg
SETZ, Christian
SCHUBERT, Ulrich
Priority Data
21000346.3   08.12.2021   EP
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2183
EPO Filing, Examination, Granting9313
Japan Filing, Examination, Granting1806
South Korea Filing, Examination, Granting1307
USA Filing, Examination, Granting4740
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Total: 19,349

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] The present application relates to a combination of 5-amino-2,3-dihydro-1,4- phthalazinedione or one of its pharmaceutically acceptable salts and a 6'-methoxycinchonan- 9-ol or a pharmaceutically acceptable salt thereof for use in the prevention or treatment of coronaviral infections. In particular, the invention relates to a combination of 5-amino-2,3- dihydro-1,4-phthalazinedione sodium salt and quinine or quinidine for said purposes. Pharmaceutical compositions and advantageous formulation techniques are disclosed.[French] La présente invention concerne une combinaison de 5-amino-2,3-dihydro-1,4-phtalazinedione ou d'un de ses sels pharmaceutiquement acceptables et d'un 6'-méthoxycinchonane-9-ol ou d'un sel pharmaceutiquement acceptable de celui-ci, destinée à être utilisée dans la prévention ou le traitement d'infections coronavirales. En particulier, l'invention concerne une combinaison de sel de sodium de 5-amino-2,3-dihydro-1,4-phtalazinedione et de quinine ou de quinidine pour lesdites applications. L'invention concerne également des compositions pharmaceutiques et des techniques de formulation avantageuses.

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