WO2026061491 - CRYSTAL FORM AND SALT FORM OF BENZOINDOLE DERIVATIVE, AND PREPARATION METHOD THEREFOR
National phase entry is expected:
Publication Number
WO/2026/061491
Publication Date
26.03.2026
International Application No.
PCT/CN2025/122635
International Filing Date
19.09.2025
Title **
[English]
CRYSTAL FORM AND SALT FORM OF BENZOINDOLE DERIVATIVE, AND PREPARATION METHOD THEREFOR
[French]
FORME CRISTALLINE ET FORME SALINE D'UN DÉRIVÉ DE BENZOINDOLE, ET SON PROCÉDÉ DE PRÉPARATION
[Chinese]
一种苯并吲哚衍生物的晶型、盐型及其制备方法
Applicants **
SHANGHAI HELIOSON PHARMACEUTICAL CO., LTD.
Inventors
ZHAO, Liwen
ZHANG, Kefeng
XU, Zheng
WANG, Dihuang
Priority Data
202411317136.5
20.09.2024
CN
Application details
| Total Number of Claims/PCT | * |
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International Searching Authority |
CNIPA
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| * | |
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 1670 | |
| EPO | Filing, Examination, Granting | 11690 | |
| Japan | Filing, Examination, Granting | 2087 | |
| South Korea | Filing, Examination, Granting | 1913 | |
| USA | Filing, Examination, Granting | 5940 |
Total:
23,300
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Abstract[English]
The present application relates to the field of pharmaceutical crystal forms, and in particular to a crystal form and salt form of a benzoindole derivative compound (formula I), a preparation method therefor, and a use thereof. Crystal form I of the obtained compound of formula I exhibits good physical and chemical stability and crystal form stability; and a preparation process thereof is simple, has good repeatability, has a high yield, is environmentally friendly and easy to operate, allows for convenient recovery, and is suitable for large-scale production.[French]
La présente invention se rapporte au domaine des formes cristallines pharmaceutiques, et concerne en particulier une forme cristalline et une forme saline d'un composé dérivé de benzoindole (formule I), son procédé de préparation et son utilisation. La forme cristalline I du composé obtenu représenté par la formule I présente une bonne stabilité physique et chimique et une bonne stabilité de forme cristalline ; et son procédé de préparation est simple, a une bonne répétabilité, a un rendement élevé, est respectueux de l'environnement et facile à utiliser, permet une récupération pratique, et est approprié pour une production à grande échelle.[Chinese]
本申请涉及药物晶型领域，具体涉及一种苯并吲哚衍生物化合物(式I)的晶型、盐型及其制备方法和用途。所得式I化合物晶型I具有较好的理化稳定性和晶型稳定性，其制备工艺简单重复性好，收率高，绿色环保，易于操作，便于回收，容易实现规模化放大生产。