WO2026057052 - IL-23 RECEPTOR INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF
National phase entry is expected:
Publication Number
WO/2026/057052
Publication Date
19.03.2026
International Application No.
PCT/CN2025/121070
International Filing Date
12.09.2025
Title **
[English]
IL-23 RECEPTOR INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF
[French]
INHIBITEUR DU RÉCEPTEUR DE L'IL-23, SON PROCÉDÉ DE PRÉPARATION ET SON UTILISATION
[Chinese]
一种IL-23受体抑制剂及其制备方法和用途
Applicants **
SHENZHEN SALUBRIS PHARMACEUTICALS CO., LTD
Inventors
LAI, Yingjie
WANG, Bin
TIAN, Zebing
YUE, Xiaoliang
XIANG, Jiehao
SU, Shaobin
ZHU, Xiaoli
XIONG, Xiaolin
XING, Wei
GE, Feng
HUANG, Hailan
Priority Data
202411296515.0
14.09.2024
CN
202411870711.4
17.12.2024
CN
202510040750.X
09.01.2025
CN
202510423935.9
03.04.2025
CN
202511227628.X
28.08.2025
CN
Application details
| Total Number of Claims/PCT | * |
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International Searching Authority |
CNIPA
* |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| * | |
| * | |
| * | |
| * | |
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2299 | |
| EPO | Filing, Examination, Granting | 13768 | |
| Japan | Filing, Examination, Granting | 2041 | |
| South Korea | Filing, Examination, Granting | 1882 | |
| USA | Filing, Examination, Granting | 5190 |
Total:
25,180
Abstract[English]
The present invention relates to the technical field of chemical drugs, and specifically relates to an IL-23 receptor inhibitor, a preparation method therefor, and a use thereof. The compound of the present invention has good IL-23 inhibitory activity, and can be used for treating inflammatory bowel disease, ulcerative colitis, Crohn's disease, psoriasis, or psoriatic arthritis. The structure of the IL-23 receptor inhibitor is as shown in general formula (I).[French]
La présente invention concerne le domaine technique des médicaments chimiques, et concerne spécifiquement un inhibiteur du récepteur de l'IL-23, son procédé de préparation et son utilisation. Le composé selon la présente invention a une bonne activité inhibitrice de l'IL-23, et peut être utilisé pour traiter une maladie intestinale inflammatoire, la rectocolite hémorragique, la maladie de Crohn, le psoriasis ou l'arthrite psoriasique. La structure de l'inhibiteur du récepteur de l'IL-23 est telle que représentée dans la formule générale (I).[Chinese]
本发明属于化学药物技术领域，具体涉及一种IL-23受体抑制剂及其制备方法和用途。本发明的化合物具有良好的IL-23抑制活性，其可用于治疗炎性肠病、溃疡性结肠炎、克罗恩氏病、银屑病、或银屑病性关节炎，所述IL-23受体抑制剂的结构如通式(I)所示。