WO2026057051 - RNAI AGENT FOR INHIBITING LPA GENE EXPRESSION IN CELLS, PREPARATION METHOD THEREFOR AND USE THEREOF

National phase entry is expected:
Publication Number WO/2026/057051
Publication Date 19.03.2026
International Application No. PCT/CN2025/121067
International Filing Date 12.09.2025
Title **
[English] RNAI AGENT FOR INHIBITING LPA GENE EXPRESSION IN CELLS, PREPARATION METHOD THEREFOR AND USE THEREOF
[French] AGENT ARNI INHIBANT L'EXPRESSION DU GÈNE LPA DANS LES CELLULES, PROCÉDÉ DE PRÉPARATION ET UTILISATION ASSOCIÉS
[Chinese] 一种用于抑制细胞中LPA基因表达的RNAi剂、其制备方法及用途
Applicants **
SHENZHEN SALUBRIS PHARMACEUTICALS CO., LTD
Inventors
JIANG, Wenjuan
ZHANG, Weiji
LI, Jiani
XIAO, Ying
LU, Yinsuo
WU, Junjun
XIONG, Xiaolin
WU, Jianli
Priority Data
202411296687.8   14.09.2024   CN
202411628965.5   13.11.2024   CN
202510435858.9   08.04.2025   CN
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2007
EPO Filing, Examination, Granting13554
Japan Filing, Examination, Granting2263
South Korea Filing, Examination, Granting2387
USA Filing, Examination, Granting4740
MasterCard Visa
Total: 24,951
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Abstract[English] Provided are an RNAi agent for inhibiting the LPA gene expression in cells, a preparation method therefor and the use thereof, and further provided is the use of the RNAi agent and a pharmaceutical composition containing the RNAi agent in the prevention or treatment of Lp(a)-related diseases.[French] La présente invention concerne un agent ARNi inhibant l'expression du gène LPA dans les cellules, un procédé de préparation afférent et son utilisation, ainsi que l'utilisation de l'agent ARNi et d'une composition pharmaceutique contenant l'agent ARNi pour la prévention ou le traitement de maladies liées à la Lp(a).[Chinese] 提供一种用于抑制细胞中LPA基因表达的RNAi剂、其制备方法及用途,还提供RNAi剂以及包含所述RNAi剂的药物组合物用于预防或治疗与Lp(a)相关疾病中的用途。

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