WO2026052028 - METHOD FOR PREPARING CAR-EXPRESSING T CELL AND USE
National phase entry is expected:
Publication Number
WO/2026/052028
Publication Date
12.03.2026
International Application No.
PCT/CN2025/119123
International Filing Date
04.09.2025
Title **
[English]
METHOD FOR PREPARING CAR-EXPRESSING T CELL AND USE
[French]
PROCÉDÉ DE PRÉPARATION D'UN LYMPHOCYTE T EXPRIMANT UN CAR ET UTILISATION
[Chinese]
一种制备表达CAR的T细胞的方法及其应用
Applicants **
SHENZHEN GENOCURY BIOTECH CO., LTD
Inventors
HUANG, Ke
LI, Yuhang
Priority Data
202411244063.1
05.09.2024
CN
Application details
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International Searching Authority |
CNIPA
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 3167 | |
| EPO | Filing, Examination, Granting | 40454 | |
| Japan | Filing, Examination, Granting | 3520 | |
| South Korea | Filing, Examination, Granting | 4894 | |
| USA | Filing, Examination, Granting | 12340 |
Total:
64,375
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Abstract[English]
The present invention relates to the field of cell therapy, and specifically relates to a method for preparing a CAR-expressing T cell and a use. Disclosed in the present invention is a method for preparing a CAR-T cell, comprising the following steps: S1, collecting a T cell-containing cell population of an autologous or allogeneic donor of a subject; S2, administering lymphodepletion therapy to the subject for pretreatment; and S3, administering the T cell-containing cell population and a viral vector to the subject.[French]
La présente invention concerne le domaine de la thérapie cellulaire, et concerne spécifiquement un procédé de préparation d'un lymphocyte T exprimant un CAR et une utilisation. La présente invention concerne un procédé de préparation d'une cellule CAR-T, comprenant les étapes suivantes : S1, la collecte d'une population de cellules contenant des lymphocytes T d'un donneur autologue ou allogénique d'un sujet ; S2, l'administration d'une thérapie par lymphodéplétion au sujet pour le prétraitement ; et S3, l'administration de la population de cellules contenant des lymphocytes T et d'un vecteur viral au sujet.[Chinese]
本领域涉及细胞疗法领域，具体涉及一种制备表达 CAR 的 T 细胞的方法及其应用。本发明公开了一种制备 CAR-T 细胞的方法，包括以下步骤：S1、采集受试者自体的或同种异体供体的包含 T 细胞的细胞群体；S2、对所述受试者施用淋巴细胞清除疗法进行预处理；和 S3、向所述受试者施用所述包含 T 细胞的细胞群体和病毒载体。