WO2026037337 - METHODS FOR PREPARING CONJUGATED COMPOUNDS AND ANTIBODY-DRUG CONJUGATES

National phase entry is expected:
Publication Number WO/2026/037337
Publication Date 19.02.2026
International Application No. PCT/CN2025/114429
International Filing Date 13.08.2025
Title **
[English] METHODS FOR PREPARING CONJUGATED COMPOUNDS AND ANTIBODY-DRUG CONJUGATES
[French] PROCÉDÉS DE PRÉPARATION DE COMPOSÉS CONJUGUÉS ET CONJUGUÉS ANTICORPS-MÉDICAMENT
Applicants **
BIOCYTOGEN PHARMACEUTICALS (BEIJING) CO., LTD.
Inventors
AN, Wenqian
HAN, Yanfei
ZHANG, Ziyang
CAO, Wenpeng
Priority Data
PCT/CN2024/111795   13.08.2024   CN
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting3386
EPO Filing, Examination, Granting38012
Japan Filing, Examination, Granting3416
South Korea Filing, Examination, Granting4747
USA Filing, Examination, Granting15190
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Total: 64,751
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Abstract[English] This disclosure relates to conjugated compounds and antibody-drug conjugates (ADCs) having a non-native cysteine residue for payload conjugation. Such conjugates may have a DAR of about 1, and can be used for diagnostic, scientific and therapeutic applications.[French] La présente divulgation concerne des composés conjugués et des conjugués anticorps-médicament (ADC) ayant un résidu cystéine non natif pour une conjugaison de charge utile. De tels conjugués peuvent avoir un DAR d'environ 1, et peuvent être utilisés pour des applications diagnostiques, scientifiques et thérapeutiques.

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