WO2026037283 - VACCINE FOR PREVENTING AND TREATING MYCOBACTERIUM TUBERCULOSIS INFECTION AND PREPARATION METHOD THEREFOR
National phase entry is expected:
Publication Number
WO/2026/037283
Publication Date
19.02.2026
International Application No.
PCT/CN2025/114100
International Filing Date
12.08.2025
Title **
[English]
VACCINE FOR PREVENTING AND TREATING MYCOBACTERIUM TUBERCULOSIS INFECTION AND PREPARATION METHOD THEREFOR
[French]
VACCIN POUR LA PRÉVENTION ET LE TRAITEMENT D'UNE INFECTION PAR MYCOBACTERIUM TUBERCULOSIS ET SON PROCÉDÉ DE PRÉPARATION
[Chinese]
一种用于预防和治疗结核分枝杆菌感染的疫苗及其制备方法
Applicants **
GUANGZHOU PATRONUS BIOTECH CO., LTD.
PATRONUS BIOTECH PTE.LTD.
Inventors
DING, Yanbin
LI, Yuanyuan
JIN, Jing
Priority Data
202411123803.6
16.08.2024
CN
Application details
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International Searching Authority |
CNIPA
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2378 | |
| EPO | Filing, Examination, Granting | 19082 | |
| Japan | Filing, Examination, Granting | 2543 | |
| South Korea | Filing, Examination, Granting | 2898 | |
| USA | Filing, Examination, Granting | 6140 |
Total:
33,041
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Abstract[English]
The present invention relates to a Mycobacterium tuberculosis vaccine. Specifically, the vaccine comprises an immune composition, and the immune composition comprises an antigen component and a particle protein component. The particle protein component comprises a nanoparticle protein, and the antigen component and the particle protein component are covalently combined by means of a binding peptide 1 and a binding peptide 2 to form an immunogenic complex. The vaccine can induce or stimulate humoral and cellular immune responses. Also disclosed is a preparation method for the Mycobacterium tuberculosis vaccine. The method is simple, cost-effective, and suitable for large-scale production.[French]
La présente invention se rapporte à un vaccin contre Mycobacterium tuberculosis. Plus particulièrement, le vaccin comprend une composition immunitaire, et la composition immunitaire comprend un composant antigène et un composant de particule de protéine. Le composant de particule de protéine comprend une nanoparticule de protéine, et le composant d'antigène et le composant de particule de protéine sont combinés de manière covalente au moyen d'un peptide de liaison 1 et d'un peptide de liaison 2 pour former un complexe immunogène. Le vaccin peut induire ou stimuler des réponses immunitaires humorales et cellulaires. L'invention divulgue également un procédé de préparation du vaccin contre Mycobacterium tuberculosis. Le procédé est simple, économique et adapté à une production à grande échelle.[Chinese]
涉及一种结核分枝杆菌疫苗，具体而言，该疫苗包含免疫组合物，所述免疫组合物包含抗原组分和颗粒蛋白组分。颗粒蛋白组分包含纳米颗粒蛋白，抗原组分与所述颗粒蛋白组分之间通过结合肽1与结合肽2共价结合，形成免疫原性复合物。该疫苗能诱导或刺激体液免疫和细胞免疫应答。还公开了所述结核分枝杆菌疫苗的制备方法，该方法操作简单、成本低，适合大规模生产。