WO2025261481 - FIVE-MEMBERED HETEROAROMATIC COMPOUND AND USE THEREOF

National phase entry is expected:
Publication Number WO/2025/261481
Publication Date 26.12.2025
International Application No. PCT/CN2025/102354
International Filing Date 20.06.2025
Title **
[English] FIVE-MEMBERED HETEROAROMATIC COMPOUND AND USE THEREOF
[French] COMPOSÉ HÉTÉROAROMATIQUE À CINQ CHAÎNONS ET SON UTILISATION
[Chinese] 五元杂芳环类化合物及其应用
Applicants **
NANJING ZAIMING PHARMACEUTICAL CO., LTD.
Inventors
YANG, Yang
ZHOU, Muxing
WANG, Juan
WANG, Weikun
SUN, Tianwen
CHEN, Lei
YU, Jian
LI, Zhengtao
TANG, Renhong
Priority Data
202410812440.0   21.06.2024   CN
202411083296.8   08.08.2024   CN
202411385008.4   30.09.2024   CN
202510050857.2   13.01.2025   CN
Application details
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Translation

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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2115
EPO Filing, Examination, Granting14045
Japan Filing, Examination, Granting2298
South Korea Filing, Examination, Granting2474
USA Filing, Examination, Granting4740
MasterCard Visa
Total: 25,672
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Abstract[English] The present disclosure provides a five-membered heteroaromatic compound represented by formula (I) or a pharmaceutically acceptable salt thereof or a stereoisomer thereof, a pharmaceutical composition containing same, and a use thereof as a WRN inhibitor in the prevention or treatment of related diseases.[French] La présente invention concerne un composé hétéroaromatique à cinq chaînons représenté par la formule (I) ou un sel pharmaceutiquement acceptable de celui-ci ou un stéréoisomère de celui-ci, une composition pharmaceutique le contenant, et son utilisation en tant qu'inhibiteur de WRN dans la prévention ou le traitement de maladies associées.[Chinese] 本公开提供了一种式(I)所示的五元杂芳环类化合物或其药学可接受的盐或其立体异构体,含有它们的药物组合物以及其作为WRN抑制剂在预防或治疗相关疾病中的应用。

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