WO2025237389 - TRICYCLIC WRN INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF
National phase entry is expected:
Publication Number
WO/2025/237389
Publication Date
20.11.2025
International Application No.
PCT/CN2025/095279
International Filing Date
16.05.2025
Title **
[English]
TRICYCLIC WRN INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF
[French]
INHIBITEUR DE WRN TRICYCLIQUE, SON PROCÉDÉ DE PRÉPARATION ET SON UTILISATION
[Chinese]
三环WRN抑制剂、其制备方法及其应用
Applicants **
CHENGDU CHIPSCREEN PHARMACEUTICAL LTD.
Inventors
WANG, Wei
LIU, Hang
LIU, Ziqiang
ZHANG, Jixin
LIU, Xiangkai
QING, Ying
ZHANG, Ping
XIE, Honglei
LUO, Xinfeng
SHAN, Song
PAN, Desi
LU, Xianping
Priority Data
202410620799.8
17.05.2024
CN
202410941402.5
12.07.2024
CN
202411213441.X
30.08.2024
CN
202411958003.6
27.12.2024
CN
Application details
| Total Number of Claims/PCT | * |
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| Number of Drawings | * |
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International Searching Authority |
CNIPA
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| * | |
| * | |
| * | |
| * | |
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
* |
| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 3390 | |
| EPO | Filing, Examination, Granting | 25146 | |
| Japan | Filing, Examination, Granting | 2763 | |
| South Korea | Filing, Examination, Granting | 3426 | |
| USA | Filing, Examination, Granting | 11440 |
Total:
46,165
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Abstract[English]
The present invention relates to a WRN inhibitor represented by formula (X), a preparation method therefor and the use thereof. The present invention further relates to a pharmaceutical composition comprising the compound as an active ingredient and the use of the compound or pharmaceutical composition for the treatment and/or prevention of diseases related to WRN biological activity.[French]
La présente invention concerne un inhibiteur de WRN représenté par la formule (X), son procédé de préparation et son utilisation. La présente invention concerne en outre une composition pharmaceutique comprenant le composé en tant que principe actif et l'utilisation du composé ou de la composition pharmaceutique pour le traitement et/ou la prévention de maladies liées à l'activité biologique de WRN.[Chinese]
本发明涉及一种式(X)所示的WRN抑制剂、其制备方法及其应用。本发明还涉及包含所述化合物作为活性成分的药物组合物以及所述化合物或药物组合物用于治疗和/或预防与WRN生物学活性相关的疾病的用途。