WO2025232711 - NEW DEUTERIUM-CONTAINING PYRAZOLONE COMPOUND, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF

National phase entry is expected:
Publication Number WO/2025/232711
Publication Date 13.11.2025
International Application No. PCT/CN2025/092791
International Filing Date 06.05.2025
Title **
[English] NEW DEUTERIUM-CONTAINING PYRAZOLONE COMPOUND, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF
[French] NOUVEAU COMPOSÉ PYRAZOLONE CONTENANT DU DEUTÉRIUM, COMPOSITION PHARMACEUTIQUE ET UTILISATION ASSOCIÉES
[Chinese] 一种新型含氘的吡唑啉酮化合物及其药物组合物和用途
Applicants **
NANJING ZHIHE MEDICINE TECHNOLOGY CO., LTD.
Inventors
ZHANG, Zhefeng
MENG, Yuelei
HOU, Wen
Priority Data
202410550297.2   06.05.2024   CN
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Translation

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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting1719
EPO Filing, Examination, Granting12297
Japan Filing, Examination, Granting1975
South Korea Filing, Examination, Granting1642
USA Filing, Examination, Granting4740
MasterCard Visa
Total: 22,373
Abstract[English] Disclosed are a new deuterium-containing pyrazolone compound, and a pharmaceutical composition and the use thereof. The new deuterium-containing pyrazolone compound is as represented by formula (I) and/or formula (II), wherein the definition of each substituent is detailed in the description. The compound can be used in the preparation of a drug for preventing or treating neurodegenerative diseases and cardiovascular and cerebrovascular diseases.[French] L'invention concerne un nouveau composé pyrazolone contenant du deutérium, une composition pharmaceutique et son utilisation. Le nouveau composé pyrazolone contenant du deutérium est tel que représenté par la formule (I) et/ou la formule (II), la définition de chaque substituant étant détaillée dans la description. Le composé peut être utilisé dans la préparation d'un médicament pour la prévention ou le traitement de maladies neurodégénératives et de maladies cardiovasculaires et cérébrovasculaires.[Chinese] 公开了一种新型含氘的吡唑啉酮化合物及其药物组合物和用途,所述新型含氘的吡唑啉酮化合物如式(I)和/或式(Ⅱ)所示,其中各取代基的定义详见说明书;该化合物可用于制备预防或治疗神经病变性疾病、心脑血管疾病的药物。

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