WO2025214476 - CBL-B INHIBITOR

National phase entry is expected:
Publication Number WO/2025/214476
Publication Date 16.10.2025
International Application No. PCT/CN2025/088516
International Filing Date 11.04.2025
Title **
[English] CBL-B INHIBITOR
[French] INHIBITEUR DE CBL-B
[Chinese] Cbl-b抑制剂
Applicants **
BEIJING INNOCARE PHARMA TECH CO., LTD.
Inventors
PANG, Yucheng
CHEN, Xiangyang
Priority Data
202410437878.5   11.04.2024   CN
Application details
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Translation

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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2808
EPO Filing, Examination, Granting16473
Japan Filing, Examination, Granting2016
South Korea Filing, Examination, Granting1794
USA Filing, Examination, Granting5640
MasterCard Visa
Total: 28,731
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Abstract[English] The present invention relates to an amide compound as a Cbl-b inhibitor or a pharmaceutically acceptable salt thereof. Specifically, the present invention relates to a compound as shown in general formula (I) or a pharmaceutically acceptable salt thereof. The present invention further relates to a method for preparing the compound or the pharmaceutically acceptable salt thereof. The compound of the present invention can be used for treating and/or preventing Cbl-b-mediated diseases, particularly cancers.[French] La présente invention concerne un composé amide utilisé en tant qu'inhibiteur de Cbl-b ou un sel pharmaceutiquement acceptable de celui-ci. Plus particulièrement, la présente invention concerne un composé tel que représenté par la formule générale (I) ou un sel pharmaceutiquement acceptable de celui-ci. La présente invention concerne en outre un procédé de préparation du composé ou du sel pharmaceutiquement acceptable de celui-ci. Le composé selon la présente invention peut être utilisé pour traiter et/ou prévenir des maladies médiées par Cbl-b, en particulier des cancers.[Chinese] 本发明涉及作为Cbl-b抑制剂的酰胺类化合物或其可药用的盐。具体而言,本发明涉及一种通式(I)所示的化合物或其可药用的盐。本发明还涉及所述化合物或其可药用的盐的制备方法。本发明的化合物可用于治疗和/或预防Cbl-b介导的疾病,特别是癌症。

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