WO2025195443 - MULTI-SPECIFIC ANTIBODY THAT SPECIFICALLY BINDS TO LIGHT AND C5A, AND COMPOSITION AND USE THEREOF

National phase entry is expected:
Publication Number WO/2025/195443
Publication Date 25.09.2025
International Application No. PCT/CN2025/083664
International Filing Date 20.03.2025
Title **
[English] MULTI-SPECIFIC ANTIBODY THAT SPECIFICALLY BINDS TO LIGHT AND C5A, AND COMPOSITION AND USE THEREOF
[French] ANTICORPS MULTI-SPÉCIFIQUE SE LIANT DE MANIÈRE SPÉCIFIQUE À LIGHT ET À C5A, COMPOSITION ET UTILISATION ASSOCIÉES
[Chinese] 特异性结合LIGHT和C5a的多特异性抗体以及组合物及其应用
Applicants **
BEIJING SOLOBIO GENETECHNOLOGY CO., LTD.
Inventors
WANG, Guangfei
LI, Zhong
FAN, Jundie
ZHANG, Si
HAN, Wuyang
ZHANG, Miaomin
WANG, Guowu
YU, Debin
CUI, Jinglan
Priority Data
PCT/CN2024/082935   21.03.2024   CN
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2349
EPO Filing, Examination, Granting17260
Japan Filing, Examination, Granting2424
South Korea Filing, Examination, Granting2550
USA Filing, Examination, Granting5140
MasterCard Visa
Total: 29,723
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Abstract[English] Provided are a multi-specific antibody or antigen-binding fragment that specifically binds to LIGHT and C5a, a composition containing an antibody or antigen-binding fragment that specifically binds to LIGHT and an antibody or antigen-binding fragment that specifically binds to C5a, a pharmaceutical composition containing the multi-specific antibody or the composition, and preparation methods therefor and the uses thereof, including a method for preventing and treating inflammatory, respiratory or autoimmune diseases by using same.[French] L'invention concerne un anticorps multi-spécifique ou un fragment de liaison à l'antigène qui se lie de manière spécifique à LIGHT et à C5a, une composition contenant un anticorps ou un fragment de liaison à l'antigène qui se lie de manière spécifique à LIGHT et un anticorps ou un fragment de liaison à l'antigène qui se lie de manière spécifique à C5a, une composition pharmaceutique contenant l'anticorps multi-spécifique ou la composition, et leurs procédés de préparation et leurs utilisations, comprenant une méthode de prévention et de traitement de maladies inflammatoires, respiratoires ou auto-immunes l'utilisant.[Chinese] 提供了特异性结合LIGHT和C5a的多特异性抗体或抗原结合片段,包含特异性结合LIGHT的抗体或抗原结合片段和特异性结合C5a的抗体或抗原结合片段的组合物,以及包含上述多特异性抗体或组合物的药物组合物、其制备方法和用途,包括用其预防和治疗炎症性、呼吸或自身免疫性疾病的方法。

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