WO2025185683 - NUCLEOTIDE FOR CONTROLLING COLEOPTERAN PESTS AND METHOD THEREFOR
National phase entry is expected:
Publication Number
WO/2025/185683
Publication Date
11.09.2025
International Application No.
PCT/CN2025/080923
International Filing Date
06.03.2025
Title **
[English]
NUCLEOTIDE FOR CONTROLLING COLEOPTERAN PESTS AND METHOD THEREFOR
[French]
NUCLÉOTIDE POUR LUTTER CONTRE LES COLÉOPTÈRES NUISIBLES ET PROCÉDÉ ASSOCIÉ
[Chinese]
用于控制鞘翅目害虫的核苷酸及其方法
Applicants **
QINGDAO KINGAGROOT SEED SCIENCE CO., LTD.
Inventors
LI, Huarong
GUO, Chenliang
LIU, Shaoyan
Priority Data
202410256708.7
06.03.2024
CN
202411958067.6
27.12.2024
CN
Application details
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International Searching Authority |
CNIPA
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 1925 | |
| EPO | Filing, Examination, Granting | 14322 | |
| Japan | Filing, Examination, Granting | 2384 | |
| South Korea | Filing, Examination, Granting | 2538 | |
| USA | Filing, Examination, Granting | 4740 |

Total:
25,909
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Abstract[English]
Provided is a method for controlling Monolepta hieroglyphica by means of using RNAi technology to reduce or silence the expression of a target gene combination in Monolepta hieroglyphica. The method selects MhCoPI gamma and Mhmi2 as target genes, designs a target sequence, and brings Monolepta hieroglyphica into contact with a corresponding dsRNA molecule, so as to inhibit the growth, development and reproduction of same and control the number of pests in the fields. Therefore, the control method is environment-friendly, efficient and safe.[French]
La présente invention concerne un procédé de lutte contre Monolepta hieroglyphica par l'utilisation de la technologie ARNi pour réduire ou inactiver l'expression d'une combinaison de gènes cibles chez Monolepta hieroglyphica. Le procédé sélectionne MhCoPI gamma et Mhmi2 comme gènes cibles, conçoit une séquence cible et met Monolepta hieroglyphica en contact avec une molécule d'ARNdb correspondante, de manière à inhiber la croissance, le développement et la reproduction de cette dernière et à limiter le nombre de ravageurs dans les champs. Le procédé de lutte contre les nuisibles est donc respectueux de l'environnement, efficace et sûr.[Chinese]
提供一种利用RNAi技术降低或关闭双斑萤叶甲体内靶标基因组合的表达来控制双斑萤叶甲的方法,选择MhCOPI gamma、Mhmi2为靶标基因,设计靶标序列,使双斑萤叶甲与相应的dsRNA分子接触,从而抑制其生长、发育和繁殖,控制害虫的田间数量,是一种环境友好、高效安全的防治方法。