WO2025180452 - WRN INHIBITOR COMPOUND AND USE THEREOF

National phase entry is expected:
Publication Number WO/2025/180452
Publication Date 04.09.2025
International Application No. PCT/CN2025/079599
International Filing Date 27.02.2025
Title **
[English] WRN INHIBITOR COMPOUND AND USE THEREOF
[French] COMPOSÉ INHIBITEUR DE WRN ET SON UTILISATION
[Chinese] WRN抑制剂化合物及其应用
Applicants **
NANJING ZAIMING PHARMACEUTICAL CO., LTD.
Inventors
WANG, Weikun
WANG, Juan
SUN, Tianwen
ZHAO, Zihao
ZHENG, Yang
WU, Jinjin
SHAN, Jinwen
ZHU, Wei
YU, Jian
LI, Zhengtao
TANG, Renhong
Priority Data
202410231931.6   29.02.2024   CN
202410332343.1   21.03.2024   CN
202410513176.0   26.04.2024   CN
202410651779.7   24.05.2024   CN
202410847628.9   27.06.2024   CN
202410998367.0   24.07.2024   CN
202411615991.4   13.11.2024   CN
Application details
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2890
EPO Filing, Examination, Granting17234
Japan Filing, Examination, Granting2366
South Korea Filing, Examination, Granting2690
USA Filing, Examination, Granting5390
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Total: 30,570
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Abstract[English] Provided in the present disclosure are a WRN inhibitor compound as shown in formula (I) or a pharmaceutically acceptable salt thereof, a pharmaceutical composition containing same, and the use thereof as a WRN inhibitor in the prevention or treatment of related diseases.[French] La présente invention concerne un composé inhibiteur de WRN tel que représenté dans la formule (I) ou un sel pharmaceutiquement acceptable de celui-ci, une composition pharmaceutique le contenant, et son utilisation en tant qu'inhibiteur de WRN dans la prévention ou le traitement de maladies associées.[Chinese] 本公开提供了一种式(I)所示的WRN抑制剂化合物或其药学可接受的盐,含有它们的药物组合物以及其作为WRN抑制剂在预防或治疗相关疾病中的应用。

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