WO2025152833 - RNA POLYMERASE VARIANT AND USE THEREOF
National phase entry is expected:
Publication Number
WO/2025/152833
Publication Date
24.07.2025
International Application No.
PCT/CN2025/071395
International Filing Date
09.01.2025
Title **
[English]
RNA POLYMERASE VARIANT AND USE THEREOF
[French]
VARIANT D'ARN POLYMÉRASE ET SON UTILISATION
[Chinese]
RNA聚合酶变体及其应用
Applicants **
NANJING VAZYME BIOTECH CO., LTD.
Inventors
XU, Xiaoyu
JIN, Qiuheng
HE, Wei
JI, Guiying
GENG, Qi
SUN, Yujian
ZHANG, Xinya
ZHOU, Hongli
Priority Data
202410777724.0
17.06.2024
CN
202410080996.5
19.01.2024
CN
Application details
| Total Number of Claims/PCT | * |
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International Searching Authority |
CNIPA
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| * | |
| * | |
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 1745 | |
| EPO | Filing, Examination, Granting | 11587 | |
| Japan | Filing, Examination, Granting | 2147 | |
| South Korea | Filing, Examination, Granting | 2074 | |
| USA | Filing, Examination, Granting | 4740 |
Total:
22,293
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Abstract[English]
Provided are an RNA polymerase variant and a preparation method therefor. The RNA polymerase variant is used in in vitro transcription to obtain an RNA product having low dsRNA contamination. In addition, provided is a method for preparing an RNA by means of in vitro transcription.[French]
L'invention concerne un variant d'ARN polymérase et son procédé de préparation. Le variant d'ARN polymérase est utilisé dans la transcription in vitro pour obtenir un produit d'ARN présentant une faible contamination par ARNdb. De plus, l'invention concerne un procédé de préparation d'un ARN au moyen d'une transcription in vitro.[Chinese]
提供一种RNA聚合酶变体及其制备方法，将所述RNA聚合酶变体用于体外转录中，可获得低dsRNA污染的RNA产物。此外，还提供了一种体外转录制备RNA的方法。