WO2025148896 - COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF TRANSMEMBRANE SERINE PROTEASE 6 (TMPRSS6)
National phase entry is expected:
Publication Number
WO/2025/148896
Publication Date
17.07.2025
International Application No.
PCT/CN2025/071152
International Filing Date
08.01.2025
Title **
[English]
COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF TRANSMEMBRANE SERINE PROTEASE 6 (TMPRSS6)
[French]
COMPOSITIONS ET PROCÉDÉS D'INHIBITION DE L'EXPRESSION DE SÉRINE PROTÉASE TRANSMEMBRANAIRE 6 (TMPRSS6)
Applicants **
SHANGHAI ARGO BIOPHARMACEUTICAL CO., LTD.
Inventors
SHU, Dongxu
SHAO, Pengcheng Patrick
XIA, Shiwei
Priority Data
PCT/CN2024/071097
08.01.2024
CN
Application details
| Total Number of Claims/PCT | * |
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International Searching Authority |
CNIPA
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 4198 | |
| EPO | Filing, Examination, Granting | 62092 | |
| Japan | Filing, Examination, Granting | 3979 | |
| South Korea | Filing, Examination, Granting | 5901 | |
| USA | Filing, Examination, Granting | 21790 |
Total:
97,960
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Abstract[English]
Compositions and methods useful to reduce expression of transmembrane serine protease 6 (TMPRSS6) gene and for treatment of TMPRSS6-associated diseases and conditions are provided. Provided are TMPRSS6 dsRNA agents, TMPRSS6 antisense polynucleotide agents, compositions comprising TMPRSS6 dsRNA agents, and compositions comprising TMPRSS6 antisense polynucleotide agents that can be used to reduce TMPRSS6 expression in cells and subjects.[French]
L'invention concerne des compositions et des procédés utiles pour réduire l'expression du gène de la sérine protéase transmembranaire 6 (TMPRSS6) et pour le traitement de maladies et d'états pathologiques associés à TMPRSS6. La présente invention concerne des agents ARNdb TMPRSS6, des agents polynucléotides antisens TMPRSS6, des compositions comportant des agents ARNdb TMPRSS6 et des compositions comportant des agents polynucléotides antisens TMPRSS6 pouvant être utilisés pour réduire l'expression de TMPRSS6 dans les cellules et les sujets.