WO2025131019 - COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF INHIBIN SUBUNIT BETA E (INHBE)

National phase entry is expected:
Publication Number WO/2025/131019
Publication Date 26.06.2025
International Application No. PCT/CN2024/140813
International Filing Date 20.12.2024
Title **
[English] COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF INHIBIN SUBUNIT BETA E (INHBE)
[French] COMPOSITIONS ET PROCÉDÉS POUR INHIBER L'EXPRESSION DE LA SOUS-UNITÉ BÊTA E DE L'INHIBINE (INHBE)
Applicants **
SHANGHAI ARGO BIOPHARMACEUTICAL CO., LTD.
Inventors
SHU, Dongxu
SHAO, Pengcheng Patrick
XIA, Shiwei
Priority Data
PCT/CN2023/140636   21.12.2023   CN
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting4343
EPO Filing, Examination, Granting66157
Japan Filing, Examination, Granting4068
South Korea Filing, Examination, Granting6097
USA Filing, Examination, Granting19390
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Total: 100,055
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Abstract[English] Compositions and methods useful to reduce expression of INHBE gene and for treatment of INHBE-associated diseases and conditions are provided. Provided are INHBE dsRNA agents, INHBE antisense polynucleotide agents, compositions comprising INHBE dsRNA agents, and compositions comprising INHBE antisense polynucleotide agents that can be used to reduce INHBE expression in cells and subjects.[French] Compositions et procédés utiles pour réduire l'expression du gène INHBE et pour le traitement des maladies et affections associées à l'INHBE. La présente invention concerne notamment des agents d'ARNdb de l'INHBE, des agents polynucléotidiques antisens de l'INHBE, des compositions comportant des agents d'ARNdb de l'INHBE et des compositions comportant des agents polynucléotidiques antisens de l'INHBE, qui peuvent être utilisés pour réduire l'expression de l'INHBE dans les cellules et les sujets.

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