WO2025130862 - NOVEL DOUBLE-STRANDED SIRNA, CONJUGATE THEREOF, AND USE THEREOF
National phase entry is expected:
Publication Number
WO/2025/130862
Publication Date
26.06.2025
International Application No.
PCT/CN2024/139907
International Filing Date
17.12.2024
Title **
[English]
NOVEL DOUBLE-STRANDED SIRNA, CONJUGATE THEREOF, AND USE THEREOF
[French]
NOUVEL ARNSI DOUBLE BRIN, SON CONJUGUÉ ET SON UTILISATION
[Chinese]
一种新型的双链siRNA、其缀合物及其用途
Applicants **
SUNSHINE LAKE PHARMA CO., LTD.
Inventors
SHU, Zhiyu
ZUO, Yinglin
CHI, Weilin
ZOU, Zhifu
XU, Honggui
CHEN, Huimeng
LI, Jing
WANG, Pu
ZENG, Liang
Priority Data
202311732910.4
18.12.2023
CN
202411056817.0
02.08.2024
CN
202411071381.2
06.08.2024
CN
Application details
| Total Number of Claims/PCT | * |
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International Searching Authority |
CNIPA
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
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Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2302 | |
| EPO | Filing, Examination, Granting | 18089 | |
| Japan | Filing, Examination, Granting | 2546 | |
| South Korea | Filing, Examination, Granting | 2821 | |
| USA | Filing, Examination, Granting | 5940 |
Total:
31,698
Abstract[English]
Provided are a novel double-stranded siRNA, a conjugate thereof and a use thereof. The double-stranded siRNA and the conjugate thereof can inhibit expression of angiotensinogen (AGT), and can be used for preparing a drug for treating and/or preventing AGT-related diseases.[French]
L'invention porte sur un nouvel ARNsi double brin, son conjugué et son utilisation. L'ARNsi double brin et son utilisation peuvent inhiber l'expression de l'angiotensinogène (AGT) et peuvent être utilisés pour préparer un médicament destiné à traiter et/ou à prévenir les maladies liées à l'AGT.[Chinese]
提供了一种新型的双链siRNA、其缀合物及其用途，所述双链siRNA及其缀合物可以抑制血管紧张素原(AGT)表达，可制备用于治疗和/或预防AGT相关疾病的药物。