WO2025103391 - SIRNA FOR INHIBITING GENE EXPRESSION OF LPA, COMPOSITION CONTAINING SAME, AND USE THEREOF
National phase entry:
Publication Number
WO/2025/103391
Publication Date
22.05.2025
International Application No.
PCT/CN2024/131910
International Filing Date
14.11.2024
Title **
[English]
SIRNA FOR INHIBITING GENE EXPRESSION OF LPA, COMPOSITION CONTAINING SAME, AND USE THEREOF
[French]
ARNSI POUR INHIBER L'EXPRESSION GÉNIQUE DE LPA, COMPOSITION LE CONTENANT ET UTILISATION ASSOCIÉE
[Chinese]
用于抑制LPA的基因表达的SIRNA，含其的组合物及其用途
Applicants **
JACORAY PHARMACEUTICAL TECHNOLOGY CO., LTD.
Inventors
ZHENG, Qian
WANG, Yanping
Priority Data
PCT/CN2023/131684
15.11.2023
CN
PCT/CN2023/137054
07.12.2023
CN
PCT/CN2024/076513
07.02.2024
CN
PCT/CN2024/083312
22.03.2024
CN
PCT/CN2024/092119
10.05.2024
CN
PCT/CN2024/093364
15.05.2024
CN
PCT/CN2024/103107
02.07.2024
CN
PCT/CN2024/113062
19.08.2024
CN
Application details
| Total Number of Claims/PCT | * |
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International Searching Authority |
CNIPA
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| * | |
| * | |
| * | |
| * | |
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 3715 | |
| EPO | Filing, Examination, Granting | 50646 | |
| Japan | Filing, Examination, Granting | 3757 | |
| South Korea | Filing, Examination, Granting | 5695 | |
| USA | Filing, Examination, Granting | 13940 |
Total:
77,753
The term for entry into the National Phase has expired. This quotation is for informational purposes only
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Abstract[English]
The present invention relates to an siRNA for inhibiting the gene expression of LPA, a composition containing same, and a use thereof. The siRNA comprises a sense strand and an antisense strand, wherein the antisense strand comprises a sequence complementary to an LPA mRNA sequence, and the sequence of the antisense strand includes a sequence of any antisense strand in Table 1.[French]
La présente invention concerne un ARNsi pour inhiber l'expression génique de LPA, une composition le contenant et une utilisation associée. L'ARNsi comprend un brin sens et un brin antisens, le brin antisens comprenant une séquence complémentaire d'une séquence d'ARNm LPA et la séquence du brin antisens comprenant une séquence de n'importe quel brin antisens du tableau 1.[Chinese]
涉及用于抑制LPA的基因表达的siRNA，含其的组合物及其用途，所述的siRNA包括正义链和反义链，其中所述的反义链包括与LPA mRNA序列互补的序列，所述反义链的序列包括表1中任一反义链的序列。