WO2025082467 - IMMUNOMODULATORS

National phase entry:
Publication Number WO/2025/082467
Publication Date 24.04.2025
International Application No. PCT/CN2024/125698
International Filing Date 18.10.2024
Title **
[English] IMMUNOMODULATORS
[French] IMMUNOMODULATEURS
[Chinese] 一种免疫调节剂
Applicants **
HITGEN INC.
Inventors
LI, Jin
BAI, Xiaoguang
HONG, Xinfu
GONG, Yi
DENG, Ning
ZHANG, Pei
QU, Qingxi
HUANG, Xiaodong
ZHANG, Rui
Priority Data
202311355692.7   19.10.2023   CN
202410006918.0   03.01.2024   CN
202410151124.3   02.02.2024   CN
202410954855.1   17.07.2024   CN
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting3412
EPO Filing, Examination, Granting17820
Japan Filing, Examination, Granting2109
South Korea Filing, Examination, Granting2075
USA Filing, Examination, Granting6090
MasterCard Visa
Total: 31,506

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] Disclosed in the present invention are immunomodulators. Specifically, the present invention relates to compounds that inhibit IL-17A and the use thereof as immunomodulators in the preparation of drugs. Disclosed in the present invention is the use of compounds represented by formula (I) or stereoisomers thereof in the preparation of drugs inhibiting IL-17A, thus providing a new option for clinically screening and/or preparing drugs for diseases related to the activity of IL-17A.[French] La présente invention concerne des immunomodulateurs. Plus particulièrement, la présente invention concerne des composés qui inhibent l'IL-17A et leur utilisation en tant qu'immunomodulateurs dans la préparation de médicaments. La présente invention concerne l'utilisation de composés représentés par la formule (I) ou des stéréoisomères de ceux-ci dans la préparation de médicaments inhibant l'IL-17A, constituant ainsi une nouvelle option pour le criblage clinique et/ou la préparation de médicaments pour des maladies liées à l'activité de l'IL-17A.[Chinese] 本发明公开了一种免疫调节剂,具体涉及一类抑制IL-17A的化合物及其作为免疫调节剂在制备药物中的用途。本发明公开了式(I)所示的化合物、或其立体异构体在制备抑制IL-17A类药物中的用途,为临床上筛选和/或制备与IL-17A活性相关的疾病的药物提供了一种新的选择。

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