WO2025021003 - AROMATIC AMIDE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF
National phase entry is expected:
Publication Number
WO/2025/021003
Publication Date
30.01.2025
International Application No.
PCT/CN2024/106286
International Filing Date
19.07.2024
Title **
[English]
AROMATIC AMIDE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF
[French]
DÉRIVÉ D'AMIDE AROMATIQUE, SON PROCÉDÉ DE PRÉPARATION ET SON UTILISATION
[Chinese]
芳香酰胺类衍生物及其制备方法和用途
Applicants **
ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.
SHANGHAI ARYL PHARMTECH CO., LTD.
Inventors
QIU, Zongxing
ZHANG, Panpan
PENG, Jilei
CAO, Hai
WANG, Zefeng
SHI, Yaqiong
YE, Cheng
XU, Daiwang
XU, Xiaojie
ZHOU, Houjiang
Priority Data
202310898800.9
21.07.2023
CN
202410417711.2
09.04.2024
CN
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
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| Number of Office Actions | * |
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International Searching Authority |
CNIPA
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| * | |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
* |
| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2489 | |
| EPO | Filing, Examination, Granting | 16414 | |
| Japan | Filing, Examination, Granting | 2327 | |
| South Korea | Filing, Examination, Granting | 2475 | |
| USA | Filing, Examination, Granting | 5190 |
Total:
28,895
The term for entry into the National Phase has expired. This quotation is for informational purposes only
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Abstract[English]
The present invention relates to an aromatic amide derivative, and a preparation method therefor, and the use of a pharmaceutical composition containing the derivative in medicine. Specifically, the present invention relates to an aromatic amide derivative as shown in general formula (I), a preparation method therefor, a pharmaceutically acceptable salt thereof, and the use thereof as a therapeutic agent, in particular a KIF18A inhibitor, wherein the definition of each group in general formula (I) is the same as the definition in the description.[French]
La présente invention concerne un dérivé d'amide aromatique, son procédé de préparation et l'utilisation d'une composition pharmaceutique contenant le dérivé en médecine. Plus particulièrement, la présente invention concerne un dérivé d'amide aromatique tel que représenté dans la formule générale (I), son procédé de préparation, un sel pharmaceutiquement acceptable de celui-ci, et son utilisation en tant qu'agent thérapeutique, en particulier un inhibiteur de KIF18A, la définition de chaque groupe dans la formule générale (I) étant la même que la définition dans la description.[Chinese]
本发明涉及一种芳香酰胺类衍生物、其制备方法及含有该衍生物的药物组合物在医药上的应用。具体而言，本发明涉及一种通式(I)所示的芳香酰胺类衍生物、其制备方法及其可药用的盐，以及它们作为治疗剂，特别是KIF18A抑制剂的用途，其中通式(I)中的各基团的定义与说明书中的定义相同。