WO2025039676 - PAN-KRAS PROTEIN TARGETED DEGRADER COMPOUND AND USE THEREOF

National phase entry is expected:
Publication Number WO/2025/039676
Publication Date 27.02.2025
International Application No. PCT/CN2024/097694
International Filing Date 06.06.2024
Title **
[English] PAN-KRAS PROTEIN TARGETED DEGRADER COMPOUND AND USE THEREOF
[French] COMPOSÉ DE DÉGRADATION CIBLÉ DE PROTÉINE PAN-KRAS ET SON UTILISATION
[Chinese] 一种靶向泛KRAS蛋白降解剂的化合物及其应用
Applicants **
BETTA PHARMACEUTICALS CO., LTD
Inventors
XU, Renqi
YANG, Xiaofeng
ZHANG, Hongbo
LU, Lu
ZHENG, Hang
WANG, Ze
WANG, Wei
LI, Shusen
HE, Jiangqi
SHI, Zhaotao
WANG, Dong
LIN, Yuanwang
LI, Tengfei
FANG, Longcheng
TAN, Yaoming
XU, Yanjie
XIA, Hongfeng
LU, Yuan
WU, Hao
ZHOU, Quan
LAN, Hong
WANG, Jiabing
DING, Lieming
Priority Data
202311043105.0   18.08.2023   CN
202311266772.5   28.09.2023   CN
202410100382.9   24.01.2024   CN
202410623723.0   17.05.2024   CN
Application details
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting5731
EPO Filing, Examination, Granting37876
Japan Filing, Examination, Granting3165
South Korea Filing, Examination, Granting4303
USA Filing, Examination, Granting12840
MasterCard Visa
Total: 63,915

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] The present invention relates to a pan-KRAS protein targeted modulator compound and the use thereof. Specifically, the present invention relates to a pan-KRAS protein targeted modulator compound as shown in general formula (A), a preparation method therefor, and the pharmaceutical use thereof.[French] La présente invention concerne un composé modulateur ciblé de protéine pan-KRAS et son utilisation. Plus particulièrement, la présente invention concerne un composé modulateur ciblé de protéine pan-KRAS tel que représenté dans la formule générale (A), son procédé de préparation et son utilisation pharmaceutique.[Chinese] 涉及一种靶向泛KRAS蛋白调节剂的化合物及其应用。具体而言,涉及一种含有通式(A)所示的靶向泛KRAS蛋白调节剂化合物、其制备方法,及其在医药上的应用。

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