WO2025175389 - COLD-TOLERANT CRISPR/CAS SYSTEMS
National phase entry is expected:
Publication Number
WO/2025/175389
Publication Date
28.08.2025
International Application No.
PCT/CA2025/050213
International Filing Date
20.02.2025
Title **
[English]
COLD-TOLERANT CRISPR/CAS SYSTEMS
[French]
SYSTÈMES CRISPR/CAS TOLÉRANTS AU FROID
Applicants **
UNIVERSITY HEALTH NETWORK
THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
THE GENERAL HOSPITAL CORPORATION D/B/A MASSACHUSETTS GENERAL HOSPITAL
KESHAVJEE, Shafique
KLEINSTIVER, Benjamin Peter
DAVIDSON, Alan Richard
CYPEL, Marcelo
MESAKI, Kumi
Inventors
KESHAVJEE, Shafique
KLEINSTIVER, Benjamin Peter
DAVIDSON, Alan Richard
CYPEL, Marcelo
MESAKI, Kumi
Priority Data
63/555,774
20.02.2024
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
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| Number of Pages with Drawings | * |
| Pages of Specification | * |
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| Number of Office Actions | * |
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International Searching Authority |
CIPO
* |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
* |
| Applicant's Legal Status |
Legal Entity
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| * | |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
* |
| Patent Delivery |
Send the Letters Patent by Courier
* |
| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 4243 | |
| EPO | Filing, Examination, Granting | 74498 | |
| Japan | Filing, Examination, Granting | 4362 | |
| South Korea | Filing, Examination, Granting | 6644 | |
| USA | Filing, Examination, Granting | 19540 |
Total:
109,287
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Abstract[English]
Provided herein are non-naturally occurring CRISPR/Cas system for modifying a genome at a cold temperature, comprising a cold-tolerant Cas effector or functional fragment thereof and a guide RNA. Also provided are methods of modifying a genome of a cell at a cold temperature.[French]
L'invention concerne un système CRISPR/Cas d'origine non naturelle pour modifier un génome à une température froide, comprenant un effecteur Cas tolérant au froid ou un fragment fonctionnel de celui-ci et un ARN guide. L'invention concerne également des procédés de modification d'un génome d'une cellule à une basse température.