WO2024184810 - ANTI-CLDN6 AND ANTI-CD3 MULTISPECIFIC ANTIBODIES AND METHODS OF USE

National phase entry:
Publication Number WO/2024/184810
Publication Date 12.09.2024
International Application No. PCT/IB2024/052124
International Filing Date 05.03.2024
Title **
[English] ANTI-CLDN6 AND ANTI-CD3 MULTISPECIFIC ANTIBODIES AND METHODS OF USE
[French] ANTICORPS MULTISPÉCIFIQUES ANTI-CLDN6 ET ANTI-CD3 ET PROCÉDÉS D'UTILISATION
Applicants **
BEONE MEDICINES I GMBH Aeschengraben 27 4051 Basel, CH
BEONE GUANGZHOU BIOLOGICS MANUFACTURING CO., LTD. No. 83 South Kangyao Road, Huangpu District, Guangzhou Guangdong, Guangdong 510555, CN
Inventors
WAN, Zhitao No. 51 Rijing Road, China Pilot Free Trade Zone, Pudong New Area Shanghai 200131, CN
LI, Dan 4F, Tower D, No. 780 Cailun Road Pilot Free Trade Zone, Pudong New Area Shanghai 201203, CN
TANG, Xiaoyan No. 30 Science Park Road, Zhongguancun Life Science Park, Changping District Beijing 102206, CN
CHEN, Yun No. 51 Rijing Road, China Pilot Free Trade Zone, Pudong New Area Shanghai 200131, CN
LEI, Ming No. 51 Rijing Road, China Pilot Free Trade Zone, Pudong New Area Shanghai 200131, CN
SHAO, Ting No. 51 Rijing Road, China Pilot Free Trade Zone, Pudong New Area Shanghai 200131, CN
XUE, Liu No. 30 Science Park Road, Zhongguancun Life Science Park, Changping District Beijing 102206, CN
DING, Yao No. 51 Rijing Road, China Pilot Free Trade Zone, Pudong New Area Shanghai 200131, CN
JI, Ruyue No. 51 Rijing Road, China Pilot Free Trade Zone, Pudong New Area Shanghai 200131, CN
XU, Qiming No. 51 Rijing Road, China Pilot Free Trade Zone, Pudong New Area Shanghai 200131, CN
GUO, Hui No. 51 Rijing Road, China Pilot Free Trade Zone, Pudong New Area Shanghai 200131, CN
Priority Data
PCT/CN2023/079805   06.03.2023   CN
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Quotation for National Phase entry

Country StagesTotal
China Filing3527
EPO Filing, Examination27072
Japan Filing535
South Korea Filing576
USA Filing, Examination14785
MasterCard Visa

Total: 46495

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] The present disclosure provides for multi-specific antibodies and antigen-binding fragments thereof that bind to human CLDN6 and CD3, a pharmaceutical composition comprising said antibody or antigen-binding fragments thereof, and use of the multi-specific antibody or antigen-binding fragments thereof or the composition for treating a disease, such as cancer.[French] La présente divulgation concerne des anticorps multi-spécifiques et des fragments de liaison à l'antigène de ceux-ci qui se lient à CLDN6 et CD3 humains, une composition pharmaceutique comprenant ledit anticorps ou des fragments de liaison à l'antigène de celui-ci, et l'utilisation de l'anticorps multi-spécifique ou de fragments de liaison à l'antigène de celui-ci ou de la composition pour le traitement d'une maladie, telle que le cancer.
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